Get the answers your EVs hold
- Walk-away automation
- Higher yield
- Higher purity
Novel EV isolation with unprecedented ease
Multidimensional isolation
- Applying physics to capture by structure, composition and size
- High purity and high yield, together
- Gentle and label-free isolation
Walk-Away Automation
- Start the run and return to isolated EVs
- Improved repeatability
- No buffers to prep or empty
Robust by Design
- Fluidics and capture in the cartridge
- No clogging or cross-contamination
- No maintenance, cleaning, or calibration
Only EVs respond to the dielectric field
Proteins and lipoproteins can overlap EVs in size, but because their structures differ, they don’t polarize the way EVs do when dielectrophoresis (DEP) is applied. We leverage these differences to selectively capture EVs. The result is gentle isolation of EVs ready for your downstream analysis.
How DEP works →Higher Yield
EV morphology and purity
The yield and purity proteomic discovery demands
Mass spectrometry on Demeter-isolated EVs from an Alzheimer's (AD) organoid model reveals significant differences.
Walk-away while Demeter EVPrep does the work
Demeter EVPrep automatically polarizes, captures, washes, and elutes your EVs, all within the cartridge. Your gently isolated EVs are label-free and ready for your discoveries.
Polarize
A non-uniform AC field induces a dipole moment selectively in EVs.
Capture & Wash
EVs are pulled to the electrode edges and washed while similarly sized proteins pass through in the flow.
Elute
Field off — EVs release into a small volume, concentrated and label-free.
Samples we can process
See the EVs you've been missing.
Talk to our team about bringing Demeter EVPrep into your lab.