Diverse Applications
Proteomic biomarker discovery
Mass spectrometry on Demeter-isolated EVs from an Alzheimer’s disease organoid model revealed significant differences between populations.
Samples: Conditioned media, CSF
See the data →Virology and diagnostic development
Demeter EVPrep isolated more EVs than SEC across all biological replicates in HIV-1 studies.
Samples: Conditioned media
See the data →Low-volume ocular samples
Reproducible EV subpopulations from small-volume, low-concentration vitreous humor samples.
Samples: Vitreous humor, aqueous humor
See the data →Respiratory biofluids
EV isolation from lung-derived biofluids with no minimum volume.
Samples: Bronchoalveolar lavage (BAL), tracheal aspirates
Use Cases
EVs ready for proteomic biomarker discovery in Alzheimer’s
Demeter EVPrep isolated EVs from wild-type (WT) and Alzheimer’s disease (AD) organoid cultures with the yield and purity mass spectrometry requires. 2,095 proteins were identified, including canonical EV, neural, and AD-relevant markers, with statistically significant differences between populations.
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Consistently more EVs for virology diagnostics
Demeter EVPrep isolated more EVs than SEC across all culture media biological replicates.
View the poster →
Unbiased capture, reproducible EV subpopulations
Vitreous humor: small volumes, low EV concentration.
Demeter EVPrep’s label-free isolation delivers reproducible EVs, run after run, with the heterogeneous EV population intact.
